Innovative milestones in Ophthalmology

An innovative era of pediatric ophthalmology and strabismus

Tuberculin in Ophthalmology Tuberculin in Ophthalmology

Milestones in Nephrology

Being the last survivor a of the original triumvirate that launched the hairpin countercurrent theory of urine concentration, I thought it might be seemly for me to reminisce about how it came about 50 years ago. In 1946, I graduated in chemistry at the University in Budapest (Hungary) and became the lucky recipient of a fellowship offered by the University of Basel (Switzerland). A few months ...

Milestones in lymphangioleiomyomatosis research.

L ymphangioleiomyomatosis (LAM), a slowly progressive disease affecting mostly young and middle-aged females [1], is one of the few orphan lung diseases that has attracted major attention in recent years from both clinicians and researchers [2], with rapidly evolving progress. With an estimated prevalence of one in 400,000 adult females aged 20–69 yrs for the sporadic form [3] and ,30% of patie...

Milestones in ataxia.

The past 25 years have seen enormous progress in the deciphering of the genetic and molecular basis of ataxias, resulting in improved understanding of their pathogenesis. The most significant milestones during this period were the cloning of the genes associated with the common spinocerebellar ataxias, ataxia telangiectasia, and Friedreich ataxia. To date, the causative mutations of more than 3...